Fries J F, Spitz P, Kraines R G, Holman H R
Arthritis Rheum. 1980 Feb;23(2):137-45. doi: 10.1002/art.1780230202.
A structure for representation of patient outcome is presented, together with a method for outcome measurement and validation of the technique in rheumatoid arthritis. The paradigm represents outcome by five separate dimensions: death, discomfort, disability, drug (therapeutic) toxicity, and dollar cost. Each dimension represents an outcome directly related to patient welfare. Quantitation of these outcome dimensions may be performed at interview or by patient questionnaire. With standardized, validated questions, similar scores are achieved by both methods. The questionnaire technique is preferred since it is inexpensive and does not require interobserver validation. These techniques appear extremely useful for evaluation of long term outcome of patients with rheumatic diseases.
本文提出了一种用于表示患者预后的结构，以及一种在类风湿性关节炎中测量预后和验证该技术的方法。该范式通过五个独立维度来表示预后：死亡、不适、残疾、药物（治疗）毒性和费用。每个维度都代表与患者福祉直接相关的一种预后。这些预后维度的量化可以在访谈时进行，也可以通过患者问卷来完成。使用标准化、经过验证的问题，两种方法都能得到相似的分数。问卷技术更受青睐，因为它成本低且不需要观察者间的验证。这些技术对于评估风湿病患者的长期预后似乎非常有用。
