Norell S E, Granström P A
Br J Ophthalmol. 1980 Feb;64(2):137-41. doi: 10.1136/bjo.64.2.137.
A recording medication monitor and fluorescein technique were used to study self-medication by 82 patients with primary open-angle glaucoma for whom pilocarpine eye drops 3 times a day had been prescribed. Of these patients 34 (41%) missed 6 or more doses during a 20-day period, and for 35 (43%) an 8-hour dose interval was exceeded at least 20% of the time. Consequences may include lack of effectiveness in preventing visual loss and unnecessary prescription of more potent, and more toxic, drugs.
使用记录式药物监测器和荧光素技术,对82例原发性开角型青光眼患者的自我用药情况进行了研究,这些患者被处方每日3次使用毛果芸香碱滴眼液。在这82例患者中,34例(41%)在20天内漏服了6剂或更多剂量,35例(43%)有至少20%的时间超过了8小时的给药间隔。后果可能包括在预防视力丧失方面缺乏效果,以及不必要地开具更强效、毒性更大的药物。