Wilson D R, Maibach H I
Biol Neonate. 1980;37(3-4):180-5. doi: 10.1159/000241271.
In vivo, noninvasive, transepidermal water loss measurements were taken from 26- to 41-week gestational age infants with a Meeco electrolytic water analyzer to yield information on the development of the function of the skin barrier. Infants 28 weeks or less have significantly greater transepidermal water loss than older gestational aged infants, thus indicating a less efficient barrier to water. Until it is known whether the decreased barrier function in premature infants also relates to percutaneous penetration, prudence is suggested in exposing such premature infants skin to chemicals.
在体内，使用Meeco电解水分分析仪对妊娠26至41周龄的婴儿进行非侵入性经表皮水分流失测量，以获取有关皮肤屏障功能发育的信息。28周及以下的婴儿经表皮水分流失明显高于孕周较大的婴儿，这表明其对水分的屏障效率较低。在明确早产儿屏障功能降低是否也与经皮渗透有关之前，建议谨慎让此类早产儿皮肤接触化学物质。
