Blackledge G, Best J J, Crowther D, Isherwood I
Clin Radiol. 1980 Mar;31(2):143-7. doi: 10.1016/s0009-9260(80)80139-5.
One hundred and thirty-six patients with biopsy proven Hodgkin's disease (HD) had conventional staging investigations and CT carried out at presentation. CT did not detect 20 out of 24 positive spleens and did not detect disease at 16 involved lymph node sites proven at laparotomy. In 60 cases in whom lymphography was performed, CT detected all disease shown by lymphography and showed additional disease in 13 other cases (three within the lymphogram area). In 43 patients CT was the only investigation of the abdomen that could be performed and identified 31 unexpected areas of disease in this group. CT altered the stage of the patients in 16% of cases compared with 8% (lymphography) and 34% (laparotomy). The importance of CT as a baseline investigation for the subsequent monitoring of the complete remission of all known disease is discussed, and the routine use of CT when available as the primary non-invasive staging investigation of the abdomen in HD is recommended.
136例经活检证实为霍奇金病（HD）的患者在初诊时接受了传统分期检查和CT检查。CT未检测出24个阳性脾脏中的20个，也未检测出剖腹探查证实的16个受累淋巴结部位的病变。在60例行淋巴造影的病例中，CT检测出淋巴造影显示的所有病变，并在其他13例病例中显示出额外病变（3例在淋巴造影片区域内）。在43例患者中，CT是唯一可进行的腹部检查，在该组中发现了31个意外的病变区域。与淋巴造影（8%）和剖腹探查（34%）相比，CT使16%的患者分期发生改变。讨论了CT作为后续监测所有已知疾病完全缓解的基线检查的重要性，并建议在可行时将CT作为HD腹部原发性非侵入性分期检查的常规手段。
