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军团病:肺纤维化和支气管肺部疾病的一个病因?(作者译)

[Legionnaires' disease: a cause of pulmonary fibrosis and bronchopulmonary disease? (author's transl)].

作者信息

Baur X, Ruckdeschel G, Fruhmann G

出版信息

Dtsch Med Wochenschr. 1980 Apr 18;105(16):561-6. doi: 10.1055/s-2008-1070706.

Abstract

Antibody titres against Legionella pneumophila (serogroups 1 and 2) were determined by the indirect immunofluorescence test on 206 patients with various forms of bronchopulmonary disease. In one third of cases there was a very weak titre (1:32 to 1:64), a moderately to markedly elevated one against one or both bacterial strains (greater than or equal to 1:128) in 4%. In one of four cases with a titre greater than or equal to 1:512 Legionnaires' disease, contracted via an air-conditioning unit, was suspected. In another case there was probably chronic Legionnaires' disease with subsequent pulmonary fibrosis. In the remaining two cases chronic Legionnaires' disease was the likely diagnosis, the clinical picture being one of nonspecific bronchopneumonia. These findings suggest that the causative organism of Legionnaires' disease is widespread also in Southern Germany and that the disease does not always lead to severe pneumonic complications.

摘要

采用间接免疫荧光试验对206例患有各种形式支气管肺部疾病的患者测定了抗嗜肺军团菌(血清群1和2)的抗体滴度。三分之一的病例滴度非常低(1:32至1:64),4%的病例针对一种或两种菌株的滴度中度至明显升高(大于或等于1:128)。在滴度大于或等于1:512的病例中,有一例怀疑是通过空调机组感染的军团病。另一例可能是慢性军团病并继发肺纤维化。其余两例可能诊断为慢性军团病,临床表现为非特异性支气管肺炎。这些发现表明,军团病的病原体在德国南部也广泛存在,而且该病并不总是导致严重的肺部并发症。

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