绿曼巴蛇毒液中的心肌抑制成分。
Myocardial depressant fraction in the venom of Dendroaspis angusticeps.
作者信息
Wangai J, Ng'ang'a J N, Mungai S, Thairu K, Telang B V
出版信息
Indian J Physiol Pharmacol. 1980 Jan-Mar;24(1):61-4.
PMID:7364462
Abstract
Whole venom Dendroaspis angusticeps produced a negative chronotropic and ionotropic effect on the heart. Isolation of the fraction (T39) produced the same effect. Negative inotropic effect was blocked by atropine. The bradycardia may be due to a cholinergic effect and the negative ionotropic to a direct depressant effect on the myocardium.
摘要
眼镜蛇毒液对心脏产生负性变时和变力作用。分离出的组分（T39）产生相同的作用。负性变力作用被阿托品阻断。心动过缓可能归因于胆碱能效应，而负性变力作用则是对心肌的直接抑制作用所致。
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