Cutts J H, Krause W J
J Anat. 1980 Jan;130(Pt 1):113-20.
Changes in the blood leukocytes have been studied in 112 opossums ranging in age from newborn to adult. Very few circulating leukocytes are present at birth, and these consist mainly of neutrophil granulocytes, with many immature forms. Leukocytes increase rapidly in number during the first 2 weeks of postnatal life, due to an accumulation of granulocytes. While all three types of granulocyte share in this early increase, initially it is the neutrophils which predominate. However, eosinophil granulocytes increase rapidly and their number soon equals or exceeds that of the neutrophils. Eosinophils remain a prominent, but lesser, component of the blood leukocytes throughout all subsequent periods of development. Lymphocytes are present only in small numbers during the first 8--10 days of postnatal life, and during this time small lymphocytes are absent from the peripheral blood. Apart from increased lobation of the granular leukocytes, the white blood cells show no remarkable cytological changes during the postnatal period.
对112只从新生到成年的负鼠的血液白细胞变化进行了研究。出生时循环白细胞很少，主要由中性粒细胞组成，有许多未成熟形式。由于粒细胞的积累，白细胞在出生后的头两周内数量迅速增加。虽然所有三种粒细胞都参与了这一早期增加，但最初占主导地位的是中性粒细胞。然而，嗜酸性粒细胞迅速增加，其数量很快等于或超过中性粒细胞。在随后的所有发育阶段，嗜酸性粒细胞一直是血液白细胞中一个突出但较少的组成部分。淋巴细胞在出生后的头8 - 10天内数量很少，在此期间外周血中没有小淋巴细胞。除了粒性白细胞的分叶增加外，白细胞在出生后期间没有明显的细胞学变化。
