Science. 1963 Jun 14;140(3572):1219-20. doi: 10.1126/science.140.3572.1219.
The production of agglutinins to Salmonella typhi was studied in the opossum embryo in the period immediately before and after the development of thymic and lymph node lymphoid tissue. Antibody was found only in embryos older than 8 days which corresponds to an 8- to 10-week human embryo in terms of organogenesis and is the earliest stage at which antibody production has been recorded.
对沙门氏菌 typhi 产生凝集素的研究是在负鼠胚胎胸腺和淋巴结淋巴组织发育前后的时期进行的。抗体仅在大于 8 天的胚胎中被发现,这相当于器官发生方面的 8-10 周人类胚胎,也是记录到抗体产生的最早阶段。