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一项收集血浆以制备人抗狂犬病免疫球蛋白的区域计划。

A regional programme to collect plasma for preparation of human immunoglobulin anti-rabies.

作者信息

Crawford R J, Morgan M, Mitchell R

出版信息

J Clin Pathol. 1980 Feb;33(2):180-2. doi: 10.1136/jcp.33.2.180.

DOI:10.1136/jcp.33.2.180
PMID:7364953
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1146017/
Abstract

We identified over 100 recipients of rabies vaccine (human diploid cell vaccine) and recruited them as plasma donors. Some were plasmapheresed at static centres, others by mobile teams. The operation of these teams is described in detail. No plasma was sent to the Fractionation Centre until the date of vaccination had been checked. Assay results showed that the majority of plasma collected between four and 20 weeks after the second dose of vaccine contained 6 or more IU/ml.

摘要

我们确定了100多名狂犬病疫苗(人二倍体细胞疫苗)接种者,并招募他们作为血浆捐献者。一些人在固定中心进行血浆采集,另一些人由流动团队采集。详细描述了这些团队的运作情况。在检查疫苗接种日期之前,没有血浆被送往分馏中心。检测结果显示,在第二剂疫苗接种后4至20周采集的大部分血浆中含有6国际单位/毫升或更多。

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1
A regional programme to collect plasma for preparation of human immunoglobulin anti-rabies.一项收集血浆以制备人抗狂犬病免疫球蛋白的区域计划。
J Clin Pathol. 1980 Feb;33(2):180-2. doi: 10.1136/jcp.33.2.180.
2
[The validation of the possibility of obtaining antirabies donor plasma].[获取抗狂犬病供血血浆可能性的验证]
Lik Sprava. 1993 Feb-Mar(2-3):65-7.
3
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[Specific and nonspecific humoral response to vaccination with the anti-rabies vaccination agents Rabivac and Vnukovo-32].[使用抗狂犬病疫苗制剂Rabivac和Vnukovo - 32进行疫苗接种后的特异性和非特异性体液反应]
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Potency requirements of rabies vaccines administered intradermally using the Thai Red Cross regimen: investigation of the immunogenicity of serially diluted purified chick embryo cell rabies vaccine.采用泰国红十字会方案皮内注射狂犬病疫苗的效价要求:连续稀释的纯化鸡胚细胞狂犬病疫苗免疫原性研究。
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Immunogenicity of purified chick embryo cell anti-rabies vaccine in post-exposure treatment of animal bite cases.纯化鸡胚细胞狂犬病疫苗在动物咬伤病例暴露后治疗中的免疫原性。
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Rhesus diploid rabies vaccine (adsorbed), a new rabies vaccine. Results of initial clinical studies of preexposure vaccination.
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本文引用的文献

1
Successful protection of humans exposed to rabies infection. Postexposure treatment with the new human diploid cell rabies vaccine and antirabies serum.成功保护暴露于狂犬病感染的人类。使用新型人二倍体细胞狂犬病疫苗和抗狂犬病血清进行暴露后治疗。
JAMA. 1976 Dec 13;236(24):2751-4.
2
Immunization against rabies with rabies immune globulin, human (RIGH) and a human diploid cell strain (HDCS) rabies vaccine.使用人狂犬病免疫球蛋白(RIGH)和人二倍体细胞株(HDCS)狂犬病疫苗进行狂犬病免疫接种。
J Biol Stand. 1978 Jul;6(3):211-9. doi: 10.1016/s0092-1157(78)80007-9.
3
Immunoglobulin (IgG) and (IgM) antibody responses to rabies vaccine.对狂犬病疫苗的免疫球蛋白(IgG)和(IgM)抗体反应。
J Gen Virol. 1978 Sep;40(3):595-604. doi: 10.1099/0022-1317-40-3-595.
4
Volume limitations of plasmapheresis.血浆置换的容量限制
Vox Sang. 1977;32(1):20-5. doi: 10.1111/j.1423-0410.1977.tb00599.x.