Bunk M J, Combs G F
J Nutr. 1980 Apr;110(4):743-9. doi: 10.1093/jn/110.4.743.
Experiments were conducted to determine the initial effects of oral selenium administration on selenium-deficient chicks. Administration of 5 microgram selenium as seleno-DL-methionine increased voluntary feed consumption within 2-3 hours, whereas selenite did not have a significant effect until 3-4 hours. Spontaneous activity, body weight gain and plasma glucose concentration increased 6-8 hours after selenium administration. The earliest response in the specific activity of selenium-dependent glutathione peroxidase occurred in plasma at 8 hours and in liver at 24 hours after selenium administration. The onset of pancreatic atrophy, however, was not affected by the level of feed intake suggesting that the effect of selenium upon appetite may be distinct from the involvement of selenium in nutritional pancreatic atrophy and fibrosis.
进行实验以确定口服硒对缺硒雏鸡的初始影响。以硒代-DL-蛋氨酸形式给予5微克硒可在2-3小时内增加自愿采食量，而亚硒酸盐直到3-4小时才有显著影响。给予硒后6-8小时，自发活动、体重增加和血浆葡萄糖浓度增加。给予硒后8小时血浆和24小时肝脏中硒依赖性谷胱甘肽过氧化物酶的比活性最早出现反应。然而，胰腺萎缩的发生不受采食量水平的影响，这表明硒对食欲的影响可能与硒在营养性胰腺萎缩和纤维化中的作用不同。
