Allen W E, Reddi R P
J Natl Med Assoc. 1980 Apr;72(4):361-70.
Gynecologic radiation oncologists have long desired a single unit by which radiation doses to specific reference points in the pelvis can be summed. The Patterns of Care Studies, Marcial's 1976 report to the Conference on Radiation Oncology of the American Cancer Society, and other radiation oncologists advise summed doses to Point A, Point B, or the pelvic side wall. Since there is a difference in the biologic effect of high intensity, long time interval teletherapy and low intensity, short time interval brachytherapy, the rad dose obtained from each modality cannot be simply added. Ellis and Sorenson in the Nominal Standard Dose (NSD) concept have described radium conversion factors that can be used to normalize brachytherapy rads at selected reference points to equivalent teletherapy rad. The two rad doses can then be summed. A simple method found useful in 50 cases of carcinoma of the cervix, and used with a computer or readily available reference tables and with any radium system, is described and discussed. Further clinical uses of the method are suggested.
长期以来，妇科放射肿瘤学家一直希望有一个单一的单位，通过它可以将骨盆中特定参考点的辐射剂量相加。“护理模式研究”、马西亚尔1976年向美国癌症协会放射肿瘤学会议提交的报告以及其他放射肿瘤学家建议将剂量相加至A点、B点或盆腔侧壁。由于高强度、长时间间隔远距离治疗与低强度、短时间间隔近距离治疗的生物学效应存在差异，因此不能简单地将从每种治疗方式获得的拉德剂量相加。埃利斯和索伦森在标称标准剂量（NSD）概念中描述了镭转换因子，这些因子可用于将选定参考点处的近距离治疗拉德剂量归一化为等效的远距离治疗拉德。然后可以将这两种拉德剂量相加。本文描述并讨论了一种在50例宫颈癌病例中发现有用的简单方法，该方法可与计算机或现成的参考表以及任何镭系统一起使用。还提出了该方法的进一步临床应用。
