Cervantes-Perez P, Toro-Perez A H, Rodriguez-Jurado P
JAMA. 1980 May 2;243(17):1715-9.
Diffuse pulmonary affection in rheumatoid arthritis remains a controversial subject that requires further and more accurate investigation. All patients with rheumatoid arthritis attending a general hospital during a six-year period underwent clinical, radiological, and functional pulmonary evaluation and serological investigation. Twenty-five had an open lung biopsy for microscopic examination and immunofluorescence. The histopathological findings in this group were correlated with the clinical, radiological, functional, and serological altercations and with the clinical course of the rheumatoid process as well. Pulmonary affection in this series was a common finding, showing definite histopathological patterns and particular clinical features.
类风湿关节炎中的弥漫性肺部病变仍是一个存在争议的课题，需要进一步且更精确的研究。在六年期间，所有到综合医院就诊的类风湿关节炎患者均接受了临床、放射学、肺功能评估及血清学检查。25例患者接受了开胸肺活检以进行显微镜检查和免疫荧光检查。该组患者的组织病理学发现与临床、放射学、功能及血清学改变相关，也与类风湿病程的临床过程相关。本系列研究中的肺部病变是一个常见发现，呈现出明确的组织病理学模式和特定的临床特征。
