Stamler J, Farinaro E, Mojonnier L M, Hall Y, Moss D, Stamler R
JAMA. 1980 May 9;243(18):1819-23.
In the Chicago Coronary Prevention Evaluation Program (CPEP), 115 men had definite mild hypertension at entry; another 101 men had high-normal diastolic blood pressure (BP). The nutritional-hygienic nonpharmacologic CPEP regimen achieved years-long moderate weight loss, slowing of pulse rate, and reduction in serum cholesterol levels. Sustained falls in BP were recorded-about 10/13 mm Hg for hypertensive men, resulting in long-term normalization of BP, and about 7/4 mm Hg for men with high-normal BP at entry. Change in weight and change in BP were significantly correlated. Long-term improvements in eating and exercise habits yielding moderate sustained weight loss are apparently useful in preventing high BP in hypertension-prone persons and in controlling established "mild" hypertension.
在芝加哥冠心病预防评估项目（CPEP）中，115名男性在入组时患有明确的轻度高血压；另有101名男性舒张压处于正常高值。CPEP营养卫生非药物治疗方案实现了长达数年的适度体重减轻、脉搏率减缓以及血清胆固醇水平降低。记录到血压持续下降——高血压男性约下降10/13毫米汞柱，从而使血压长期正常化，入组时舒张压处于正常高值的男性约下降7/4毫米汞柱。体重变化与血压变化显著相关。长期改善饮食和运动习惯，实现适度持续体重减轻，显然有助于预防易患高血压人群患高血压，并控制已确诊的“轻度”高血压。
