• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

弥漫性肺纤维化与食管裂孔疝的关联:纯属巧合?(作者译)

[The association of diffuse pulmonary fibrosis and hiatal hernia: a simple coincidence? (author's transl)].

作者信息

Sauret J, Casán P

出版信息

Med Clin (Barc). 1980 Mar 25;74(6):235-8.

PMID:7366285
Abstract

Gastroesophageal diseases with reflux can cause numerous pulmonary complications (bronchospasm crisis, bronchitis, pneumonias, lung abscesses). These manifestations are very frequent in the hiatal hernias and in some series have reached up to 46 percent of the cases studied. Recently it has been suggested that microaspirations, repeated over a long period of time, may cause an alteration of the pulmonary interstitium and the consecutive development of a clinical and roentgenologic picture similar to pulmonary fibrosis. The aspirations are produced more frequently at night, favoured by the lying down position and because of it the patients present attacks of nocturnal cough. In this paper, two patients who presented the association of pulmonary fibrosis and hiatal hernia with esophageal relux are described. The first case was diagnosed early; he had minimal radiographic anomalies and the disappearance of the respiratory symptomatology was achieved by means of the medical treatment of the esophageal reflux. The second case was in a very advanced stage with severe respiratory insufficiency and gastrointestinal manifestations of many years' evolution. Both patients had been diagnosed as having idiopathic pulmonary fibrosis. Although there is no experimental proof of the "reflux-fibrosis" theory, we think that this possibility should be kept in mind before diagnosing the interstitial pulmonary pattern as idiopathic, especially in the cases of only slight radiographic and functional involvement susceptible to improvement with correction of the esophageal reflux.

摘要

伴有反流的胃食管疾病可引发多种肺部并发症(支气管痉挛危象、支气管炎、肺炎、肺脓肿)。这些表现在食管裂孔疝中非常常见,在某些系列研究中,在所研究的病例中发生率高达46%。最近有人提出,长期反复的微量误吸可能导致肺间质改变,并继而出现类似于肺纤维化的临床和影像学表现。误吸在夜间更频繁发生,平躺姿势会促使其发生,因此患者会出现夜间咳嗽发作。本文描述了两名患有肺纤维化且伴有食管裂孔疝和食管反流的患者。第一例患者诊断较早;其影像学异常轻微,通过食管反流的药物治疗,呼吸道症状消失。第二例患者处于非常晚期,有严重的呼吸功能不全以及多年演变而来的胃肠道表现。两名患者均曾被诊断为特发性肺纤维化。尽管“反流 - 纤维化”理论尚无实验证据,但我们认为,在将间质性肺疾病模式诊断为特发性之前,尤其是在仅存在轻微影像学和功能受累且通过纠正食管反流可能改善的情况下,应考虑这种可能性。

相似文献

1
[The association of diffuse pulmonary fibrosis and hiatal hernia: a simple coincidence? (author's transl)].弥漫性肺纤维化与食管裂孔疝的关联:纯属巧合?(作者译)
Med Clin (Barc). 1980 Mar 25;74(6):235-8.
2
Pulmonary fibrosis associated with tracheobronchial aspiration. A study of the frequency of hiatal hernia and gastroesophageal reflux in interstitial pulmonary fibrosis of obscure etiology.
Chest. 1976 Apr;69(4):512-5. doi: 10.1378/chest.69.4.512.
3
[Bronchopulmonary manifestations of gastroesophageal reflux].[胃食管反流的支气管肺表现]
Rev Ig Bacteriol Virusol Parazitol Epidemiol Pneumoftiziol Pneumoftiziol. 1979 Jul-Sep;28(3):137-46.
4
[Diffuse interstitial pneumopathy and hiatal hernia].[弥漫性间质性肺病与食管裂孔疝]
Poumon Coeur. 1977;33(6):361-3.
5
Gastroesophageal reflux disease and patterns of reflux in patients with idiopathic pulmonary fibrosis using hypopharyngeal multichannel intraluminal impedance.使用下咽多通道腔内阻抗检测特发性肺纤维化患者的胃食管反流病及反流模式
Dis Esophagus. 2014 Aug;27(6):530-7. doi: 10.1111/j.1442-2050.2012.01446.x. Epub 2012 Oct 26.
6
The incidence of sliding hiatal hernias in patients with gastroesophageal reflux requiring operation.需要手术治疗的胃食管反流患者中滑动性食管裂孔疝的发病率。
Acta Chir Scand. 1983;149(1):63-7.
7
[Hiatal hernia in infants and children with special reference to pulmonary complications and reflux esophagitis (author's transl)].
Nihon Igaku Hoshasen Gakkai Zasshi. 1979 Jun 25;39(6):605-10.
8
[Pulmonary complications of hiatus hernia of sliding type (author's transl)].
Ann Chir. 1976 Mar;30(3):215-8.
9
[Hiatal hernia following T.E.F. repair (author's transl)].食管气管瘘修复术后的食管裂孔疝(作者译)
An Esp Pediatr. 1979 Nov;12(11):791-6.
10
Hiatal hernia on thoracic computed tomography in pulmonary fibrosis.肺纤维化患者的胸部 CT 检查中的膈疝。
Eur Respir J. 2016 Sep;48(3):833-42. doi: 10.1183/13993003.01796-2015. Epub 2016 May 12.

引用本文的文献

1
Anti-acid treatment and disease progression in idiopathic pulmonary fibrosis: an analysis of data from three randomised controlled trials.抗酸治疗与特发性肺纤维化的疾病进展:三项随机对照试验数据分析。
Lancet Respir Med. 2013 Jul;1(5):369-76. doi: 10.1016/S2213-2600(13)70105-X. Epub 2013 Jun 14.