Orgel L E, Crick F H
Nature. 1980 Apr 17;284(5757):604-7. doi: 10.1038/284604a0.
The DNA of higher organisms usually falls into two classes, one specific and the other comparatively nonspecific. It seems plausible that most of the latter originates by the spreading of sequences which had little or no effect on the phenotype. We examine this idea from the point of view of the natural selection of preferred replicators within the genome.
高等生物的DNA通常分为两类，一类是特异性的，另一类是相对非特异性的。后者中的大多数似乎是由对表型影响很小或没有影响的序列扩散产生的，这似乎是合理的。我们从基因组内优先复制子的自然选择角度来审视这一观点。
