皮质醇与胰腺分泌。对纯胰液的观察。

Cortisol and pancreatic secretion. Observations on pure pancreatic juice.

作者信息

Gullo L, Costa P L, Tessari R, Fontana G

出版信息

Scand J Gastroenterol. 1980;15(1):45-7. doi: 10.3109/00365528009181430.

Abstract

In view of the conflicting results in the literature, we undertook a study of the effects of intravenous administration of control on the external secretion of the pancreas. The study was carried out in five subjects with external transduodenal drainage of the main pancreatic duct, performed after biliary tract surgery. The intravenous injection of cortisol, 100 mg, during a constant intravenous infusion of secretin and cholecystokinin did not cause any significant change in pancreatic secretion. The results do not confirm previous findings in man indicating an inhibitory effect of glucocorticoids given intravenously on exocrine pancreatic secretion.

摘要

鉴于文献中的结果相互矛盾，我们开展了一项关于静脉注射对照物对胰腺外分泌作用的研究。该研究在5名接受胆道手术后进行了主胰管十二指肠外引流的受试者中开展。在持续静脉输注促胰液素和胆囊收缩素期间静脉注射100mg皮质醇，并未引起胰腺分泌的任何显著变化。这些结果并未证实之前在人体中的研究结果，即静脉给予糖皮质激素对外分泌性胰腺分泌具有抑制作用。