使用森德希尔株和RA 27/3株风疹疫苗接种后淋巴细胞对植物血凝素反应性的抑制
Suppression of lymphocyte PHA-responsiveness after rubella vaccination with Cendehill and RA 27/3 strains.
作者信息
Vesikari T
出版信息
Scand J Infect Dis. 1980;12(1):7-11. doi: 10.3109/inf.1980.12.issue-1.02.
Abstract
Two rubella vaccine strains, Cendehill and RA 27/3, were compared with regard to their immunosuppressive effect in vivo. 26 female vaccinees were studied. Both vaccines caused a slight transient suppression of lymphocyte responsiveness to mitogens on day 11 after vaccination. A whole blood culture method was used for lymphocyte stimulation tests, and the method appeared suitable for clinical studies of cell-mediated immunity.
摘要
对两种风疹疫苗株Cendehill和RA 27/3在体内的免疫抑制作用进行了比较。对26名女性接种者进行了研究。两种疫苗在接种后第11天均引起淋巴细胞对丝裂原反应性的轻微短暂抑制。采用全血培养法进行淋巴细胞刺激试验，该方法似乎适用于细胞介导免疫的临床研究。
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