• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

周围神经修复后肌肉与前角运动神经元之间连接的改变。

Alteration in connections between muscle and anterior horn motoneurons after peripheral nerve repair.

作者信息

Brushart T M, Mesulam M M

出版信息

Science. 1980 May 9;208(4444):603-5. doi: 10.1126/science.7367884.

DOI:10.1126/science.7367884
PMID:7367884
Abstract

The connections between the spinal cord and lower leg muscles of the rat are significantly altered by repair of the intervening sciatric nerve. Muscles supplied by the peroneal branch of the sciatic are innervated by fewer motoneurons after sciatic repair. Many of these neurons originally innervated the peroneal muscles, and others formerly served the antagonistic tibial muscles. Perikarya in the size range of alpha motoneurons regained peripheral connections with greater frequency than those in the gamma range. There are thus postoperative defects in the extent and specificity of alpha reinnervation as well as in the degree of gamma control.

摘要

大鼠脊髓与小腿肌肉之间的连接会因坐骨神经的修复而发生显著改变。坐骨神经腓总分支所支配的肌肉在坐骨神经修复后,由较少的运动神经元支配。这些神经元中许多原本支配腓骨肌,其他一些则曾支配拮抗的胫骨肌。α运动神经元大小范围内的神经元胞体比γ运动神经元大小范围内的神经元胞体更频繁地重新建立外周连接。因此,术后α运动神经元再支配的范围和特异性以及γ运动神经元控制程度都存在缺陷。

相似文献

1
Alteration in connections between muscle and anterior horn motoneurons after peripheral nerve repair.周围神经修复后肌肉与前角运动神经元之间连接的改变。
Science. 1980 May 9;208(4444):603-5. doi: 10.1126/science.7367884.
2
Specificity of muscle reinnervation after epineurial and individual fascicular suture of the rat sciatic nerve.大鼠坐骨神经束膜缝合与单束缝合后肌肉再支配的特异性
J Hand Surg Am. 1983 May;8(3):248-53. doi: 10.1016/s0363-5023(83)80152-x.
3
The fate of motoneurons in the spinal cord after peripheral nerve repair: a quantitative study using the neural tracer horseradish peroxidase.周围神经修复后脊髓运动神经元的命运:一项使用神经示踪剂辣根过氧化物酶的定量研究。
J Neurosurg. 1995 Apr;82(4):623-9. doi: 10.3171/jns.1995.82.4.0623.
4
Coordination of reinnervated muscle and reorganization of spinal cord motoneurons after nerve transection in mice.小鼠神经横断后再支配肌肉的协调及脊髓运动神经元的重组
Brain Res. 1990 May 7;515(1-2):241-6. doi: 10.1016/0006-8993(90)90602-8.
5
[The topographical localization of spinal motoneurons of the rat and its numerical alternation in regard to development (author's transl)].大鼠脊髓运动神经元的局部定位及其在发育过程中的数量变化(作者译)
Nihon Seikeigeka Gakkai Zasshi. 1979 Jul;53(7):807-16.
6
The organization of motoneurons in the turtle lumbar spinal cord.乌龟腰脊髓中运动神经元的组织
J Comp Neurol. 1984 Sep 1;228(1):24-37. doi: 10.1002/cne.902280105.
7
Reconstruction of peripheral nerves: the phenomenon of bilateral reinnervation of muscles originally innervated by unilateral motoneurons.周围神经重建:最初由单侧运动神经元支配的肌肉出现双侧再支配现象。
Neurosurgery. 1992 Mar;30(3):364-8; discussion 368-9. doi: 10.1227/00006123-199203000-00009.
8
[Reinnervation after direct neurotization in cross innervated rats--a study of spinal anterior horn cells by horseradish peroxidase method].[交叉神经支配大鼠直接神经吻合后的再支配——辣根过氧化物酶法对脊髓前角细胞的研究]
Nihon Seikeigeka Gakkai Zasshi. 1992 Dec;66(12):1255-65.
9
Crossing dendrites may be a substrate for synchronized activation of penile motoneurons.交叉的树突可能是阴茎运动神经元同步激活的一个底物。
Brain Res. 1985 Jul 1;337(2):373-7. doi: 10.1016/0006-8993(85)90078-2.
10
A reassessment of the accuracy of reinnervation by motoneurons following crushing or freezing of the sciatic or lumbar spinal nerves of rats.对大鼠坐骨神经或腰脊髓神经挤压或冷冻后运动神经元再支配准确性的重新评估。
Brain. 1987 Jun;110 ( Pt 3):695-705. doi: 10.1093/brain/110.3.695.

引用本文的文献

1
Soleus H-Reflex Up-Conditioning during Sciatic Nerve Regeneration in Rats Improves Recovery of Locomotion.大鼠坐骨神经再生过程中比目鱼肌H反射上调调节可改善运动恢复。
bioRxiv. 2025 Jul 3:2024.12.09.627519. doi: 10.1101/2024.12.09.627519.
2
Preferential motor reinnervation is modulated by both repair site and distal nerve environments.优先运动神经再支配受修复部位和远端神经环境的调节。
Exp Neurol. 2025 Mar;385:115066. doi: 10.1016/j.expneurol.2024.115066. Epub 2024 Nov 21.
3
Clinical Evidence of Retrograde Axonal Growth in Chronic Brachial Plexus Injury.
慢性臂丛神经损伤中轴突逆行生长的临床证据
Cureus. 2024 Jun 15;16(6):e62424. doi: 10.7759/cureus.62424. eCollection 2024 Jun.
4
Interpretation of Data from Translational Rodent Nerve Injury and Repair Models.转化型啮齿动物神经损伤与修复模型的数据解读。
Hand Clin. 2024 Aug;40(3):429-440. doi: 10.1016/j.hcl.2024.03.004. Epub 2024 May 19.
5
Modulation of central synapse remodeling after remote peripheral injuries by the CCL2-CCR2 axis and microglia.CCL2-CCR2 轴和小胶质细胞对远程外周损伤后中枢突触重构的调节。
Cell Rep. 2024 Feb 27;43(2):113776. doi: 10.1016/j.celrep.2024.113776. Epub 2024 Feb 15.
6
Brief Electrical Stimulation Promotes Recovery after Surgical Repair of Injured Peripheral Nerves.短暂电刺激促进周围神经损伤修复术后的恢复。
Int J Mol Sci. 2024 Jan 4;25(1):665. doi: 10.3390/ijms25010665.
7
Late Results of Early End-to-End Repair in Sciatic Nerve Injuries.坐骨神经损伤早期端端修复的远期疗效
Cureus. 2023 Oct 16;15(10):e47101. doi: 10.7759/cureus.47101. eCollection 2023 Oct.
8
Massive Loss of Proprioceptive Ia Synapses in Rat Spinal Motoneurons after Nerve Crush Injuries in the Postnatal Period.出生后时期神经挤压损伤后大鼠脊髓运动神经元中本体感受 Ia 突触的大量丧失。
eNeuro. 2023 Feb 16;10(2). doi: 10.1523/ENEURO.0436-22.2023. Print 2023 Feb.
9
Trigeminal Sensory Supply Is Essential for Motor Recovery after Facial Nerve Injury.三叉神经感觉供应对面神经损伤后运动功能的恢复至关重要。
Int J Mol Sci. 2022 Dec 1;23(23):15101. doi: 10.3390/ijms232315101.
10
The Role of Microglia in Neuroinflammation of the Spinal Cord after Peripheral Nerve Injury.小胶质细胞在周围神经损伤后脊髓神经炎症中的作用。
Cells. 2022 Jun 30;11(13):2083. doi: 10.3390/cells11132083.