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凝集素对人单核细胞组织凝血活酶活性的体外刺激作用。

Lectin stimulation of tissue thromboplastin activity in human monocytes in vitro.

作者信息

Lyberg T, Prydz H

出版信息

Thromb Haemost. 1980 Feb 29;42(5):1574-9.

PMID:7368158
Abstract

Lectins (phytohaemagglutinin, concanavalin A and wheat germ agglutinin) trigger an increase in tissue thromboplastin activity of human monocytes in vitro. The presence of serum was not necessary and did not enhance the activity. The increase was inhibited by cycloheximide and actinomycin D, suggesting that de novo protein synthesis is involved.

摘要

凝集素（植物血凝素、伴刀豆球蛋白A和麦胚凝集素）在体外可引发人单核细胞组织凝血活酶活性增加。血清并非必需，且不会增强该活性。这种增加受到放线菌酮和放线菌素D的抑制，提示涉及从头合成蛋白质。

相似文献

1
Lectin stimulation of tissue thromboplastin activity in human monocytes in vitro.凝集素对人单核细胞组织凝血活酶活性的体外刺激作用。
Thromb Haemost. 1980 Feb 29;42(5):1574-9.
2
Inhibition of human lymphocyte proliferation by the nonmitogenic lectin wheat germ agglutinin.非促有丝分裂凝集素麦胚凝集素对人淋巴细胞增殖的抑制作用。
J Immunol. 1980 Jun;124(6):2979-87.
3
Early activation events in lectin-stimulated human lymphocytes: evidence that wheat germ agglutinin and mitogenic lectins cause similar early changes in lymphocyte metabolism.凝集素刺激的人淋巴细胞中的早期激活事件：小麦胚芽凝集素和促有丝分裂凝集素在淋巴细胞代谢中引起相似早期变化的证据。
J Immunol. 1980 Oct;125(4):1544-50.
4
Lectin Stimulation of Tissue Thromboplastin Activity in Human Monocytes in vitro.凝集素对人单核细胞组织凝血活酶活性的体外刺激作用
Thromb Haemost. 1979 Jul;42(1):1574-1579. doi: 10.1055/s-0038-1657060. Epub 2019 Feb 18.
5
The activation of blast transformation and DNA synthesis in human peripheral blood lymphocytes by wheat germ agglutinin.麦胚凝集素对人外周血淋巴细胞的胚细胞转化和DNA合成的激活作用。
J Immunol. 1980 Aug;125(2):814-9.
6
Opposing effects of mitogenic and nonmitogenic lectins on lymphocyte activation. Evidence that wheat germ agglutinin produces a negative signal.促有丝分裂和非促有丝分裂凝集素对淋巴细胞激活的相反作用。小麦胚凝集素产生负信号的证据。
J Biol Chem. 1976 Jul 10;251(13):4017-25.
7
In vitro influence of Phaseolus vulgaris, Griffonia simplicifolia, concanavalin A, wheat germ, and peanut agglutinins on HCT-15, LoVo, and SW837 human colorectal cancer cell growth.菜豆、西非凤凰木、伴刀豆球蛋白A、小麦胚芽和花生凝集素对HCT - 15、LoVo和SW837人结肠癌细胞生长的体外影响。
Gut. 1997 Feb;40(2):253-61. doi: 10.1136/gut.40.2.253.
8
Platelets stimulate thromboplastin synthesis in human endothelial cells.血小板刺激人内皮细胞中凝血活酶的合成。
Thromb Haemost. 1983 Apr 28;49(2):69-72.
9
Reversible inhibition of the in vitro coagulation of human plasma by lectins.凝集素对人血浆体外凝血的可逆抑制作用。
Thromb Haemost. 1982 Oct 29;48(2):120-4.
10
Electron microscope assessment of fertilization of rabbit ova treated with concanavalin A and wheat germ agglutinin.用伴刀豆球蛋白A和麦胚凝集素处理的兔卵子受精的电子显微镜评估
J Exp Zool. 1976 Dec;198(3):437-42. doi: 10.1002/jez.1401980319.

引用本文的文献

1
Direct induction of tissue factor synthesis by endotoxin in human macrophages from diverse anatomical sites.内毒素对来自不同解剖部位的人巨噬细胞组织因子合成的直接诱导作用。
Immunology. 1983 Dec;50(4):529-35.
2
Phorbol esters induce synthesis of thromboplastin activity in human monocytes.佛波酯可诱导人单核细胞中凝血活酶活性的合成。
Biochem J. 1981 Mar 15;194(3):699-706. doi: 10.1042/bj1940699.
3
Thromboplastin (tissue factor) in plasma membranes of human monocytes.人单核细胞膜中的凝血活酶（组织因子）。
Biochem J. 1985 Jun 15;228(3):735-43. doi: 10.1042/bj2280735.
4
Effect of cyclosporine A on procoagulant activity in mononuclear blood cells and monocytes in vitro.环孢素A对体外单个核血细胞和单核细胞促凝血活性的影响。
Clin Exp Immunol. 1985 May;60(2):407-16.