凝集素对人单核细胞组织凝血活酶活性的体外刺激作用。
Lectin stimulation of tissue thromboplastin activity in human monocytes in vitro.
作者信息
Lyberg T, Prydz H
出版信息
Thromb Haemost. 1980 Feb 29;42(5):1574-9.
PMID:7368158
Abstract
Lectins (phytohaemagglutinin, concanavalin A and wheat germ agglutinin) trigger an increase in tissue thromboplastin activity of human monocytes in vitro. The presence of serum was not necessary and did not enhance the activity. The increase was inhibited by cycloheximide and actinomycin D, suggesting that de novo protein synthesis is involved.
摘要
凝集素（植物血凝素、伴刀豆球蛋白A和麦胚凝集素）在体外可引发人单核细胞组织凝血活酶活性增加。血清并非必需，且不会增强该活性。这种增加受到放线菌酮和放线菌素D的抑制，提示涉及从头合成蛋白质。
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