Frenckner B, Molander M L
Acta Paediatr Scand. 1980 Jan;69(1):73-7. doi: 10.1111/j.1651-2227.1980.tb07033.x.
Manometric recordings of the internal anal sphincter activity are frequently used in the diagnosis of Hirschprung's disease. Normally, there is a relaxation of the internal sphincter in response to a rectal distension, but this is absent in Hirschprung's disease. In order to study the normal physiology during the first days of life, 17 healthy full-term infants were examined daily with ano-rectal manometry during the first four days of life. Resting anal pressure was lower than in older children. Internal sphincter relaxation was recorded in all infants but one on the first day, in all on the second and finally in all but one on the third and fourth days. The results indicate that anorectal manometry may be used in the diagnosis of Hirschprung's disease also in the newborn period. However, repeated examinations may be necessary and the diagnostic reliability may be somewhat lower than in older children.
肛门内括约肌活动的测压记录常用于先天性巨结肠病的诊断。正常情况下，直肠扩张时内括约肌会松弛，但先天性巨结肠病患者不存在这种情况。为了研究生命最初几天的正常生理状况，对17名健康足月儿在出生后的头四天每天进行肛门直肠测压检查。静息肛门压力低于大龄儿童。除一名婴儿外，所有婴儿在第一天均记录到内括约肌松弛，第二天所有婴儿均记录到，第三天和第四天除一名婴儿外所有婴儿均记录到。结果表明，肛门直肠测压也可用于新生儿期先天性巨结肠病的诊断。然而，可能需要重复检查，且诊断可靠性可能略低于大龄儿童。
