• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Effect of oxygenated sterols on 3-hydroxy-3-methylglutaryl coenzyme A reductase and DNA synthesis in phytohemagglutinin-stimulated human lymphocytes.

作者信息

Astruc M, Laporte M, Tabacik C, Crastes de Paulet A

出版信息

Biochem Biophys Res Commun. 1978 Nov 29;85(2):691-700. doi: 10.1016/0006-291x(78)91217-2.

DOI:10.1016/0006-291x(78)91217-2
PMID:736927
Abstract
摘要

相似文献

1
Effect of oxygenated sterols on 3-hydroxy-3-methylglutaryl coenzyme A reductase and DNA synthesis in phytohemagglutinin-stimulated human lymphocytes.氧化甾醇对植物血凝素刺激的人淋巴细胞中3-羟基-3-甲基戊二酰辅酶A还原酶及DNA合成的影响。
Biochem Biophys Res Commun. 1978 Nov 29;85(2):691-700. doi: 10.1016/0006-291x(78)91217-2.
2
Relationship between sterol synthesis and DNA synthesis in phytohemagglutinin-stimulated mouse lymphocytes.植物血凝素刺激的小鼠淋巴细胞中固醇合成与DNA合成之间的关系。
Proc Natl Acad Sci U S A. 1975 May;72(5):1950-4. doi: 10.1073/pnas.72.5.1950.
3
Inhibitors of sterol synthesis. Chemical syntheses, properties and effects of 4,4-dimethyl-15-oxygenated sterols on sterol synthesis and on 3-hydroxy-3-methylglutaryl coenzyme A reductase activity in cultured mammalian cells.甾醇合成抑制剂。4,4-二甲基-15-氧化甾醇在培养的哺乳动物细胞中对甾醇合成及3-羟基-3-甲基戊二酰辅酶A还原酶活性的化学合成、性质及作用。
Chem Phys Lipids. 1988 Jul;47(3):187-207. doi: 10.1016/0009-3084(88)90012-6.
4
Use of oxygenated sterols to probe the regulation of 3-hydroxy-3-methylglutaryl-CoA reductase and sterologenesis.利用氧化甾醇探究3-羟基-3-甲基戊二酰辅酶A还原酶的调控及甾醇生成。
Methods Enzymol. 1985;110:9-19. doi: 10.1016/s0076-6879(85)10055-8.
5
Comparative study of the kinetics of 3-hydroxy-3-methylglutaryl coenzyme A reductase and [14C]-acetate incorporation into cholesterol in human lymphocytes stimulated by phytohemagglutinin or sterol efflux.3-羟基-3-甲基戊二酰辅酶A还原酶动力学与[14C] - 乙酸盐掺入经植物血凝素刺激或甾醇流出的人淋巴细胞中胆固醇的比较研究
Biomedicine. 1981 Dec;34(3):128-32.
6
DNA synthesis and 3-hydroxy-3-methylglutaryl CoA reductase activity in PHA stimulated human lymphocytes: a comparative study of the inhibitory effects of some oxysterols with special reference to side chain hydroxylated derivatives.PHA刺激的人淋巴细胞中的DNA合成及3-羟基-3-甲基戊二酰辅酶A还原酶活性：某些氧化甾醇抑制作用的比较研究，特别提及侧链羟基化衍生物
Biochem Biophys Res Commun. 1982 May 31;106(2):362-72. doi: 10.1016/0006-291x(82)91118-4.
7
Feedback regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase in vascular endothelial cells. Separate sterol and non-sterol components.血管内皮细胞中3-羟基-3-甲基戊二酰辅酶A还原酶的反馈调节。固醇和非固醇成分各自独立。
J Biol Chem. 1982 Sep 25;257(18):11106-12.
8
Cholesterol biosynthesis and 3-hydroxy-3-methyl-glutaryl coenzyme A reductase in cultured glial and neuronal cells. Regulation by lipoprotein and by certain free sterols.培养的神经胶质细胞和神经元细胞中的胆固醇生物合成及3-羟基-3-甲基戊二酰辅酶A还原酶。脂蛋白和某些游离固醇的调节作用。
Biochim Biophys Acta. 1977 Mar 25;486(3):408-20. doi: 10.1016/0005-2760(77)90090-x.
9
Regulation of sterol synthesis in human lymphocytes: evidence for post-transcriptional control by low density lipoprotein.人类淋巴细胞中固醇合成的调控：低密度脂蛋白进行转录后调控的证据。
Biochim Biophys Acta. 1979 Aug 30;574(2):361-5. doi: 10.1016/0005-2760(79)90018-3.
10
Correlation among oxysterol potencies in the regulation of the degradation of 3-hydroxy-3-methylglutaryl CoA reductase, the repression of 3-hydroxy-3-methylglutaryl CoA synthase and affinities for the oxysterol receptor.氧化甾醇在调节3-羟基-3-甲基戊二酰辅酶A还原酶降解、抑制3-羟基-3-甲基戊二酰辅酶A合酶以及与氧化甾醇受体亲和力方面的效力之间的相关性。
Biochem Biophys Res Commun. 1992 Jul 15;186(1):182-9. doi: 10.1016/s0006-291x(05)80791-0.

引用本文的文献

1
Neurotoxicity of 25-OH-cholesterol on NGF-differentiated PC12 cells.25-羟基胆固醇对经神经生长因子分化的PC12细胞的神经毒性作用。
Neurochem Res. 1998 Jan;23(1):7-16. doi: 10.1023/a:1022437000893.
2
Side-chain oxysterol regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity.侧链氧化甾醇对3-羟基-3-甲基戊二酰辅酶A还原酶活性的调节
Lipids. 1995 Mar;30(3):247-51. doi: 10.1007/BF02537828.
3
Apoptosis induced by oxysterols in murine lymphoma cells and in normal thymocytes.氧化甾醇在小鼠淋巴瘤细胞和正常胸腺细胞中诱导的细胞凋亡。
Immunology. 1993 Mar;78(3):455-60.
4
Inhibition by ketoconazole of mitogen-induced DNA synthesis and cholesterol biosynthesis in lymphocytes.酮康唑对淋巴细胞中丝裂原诱导的DNA合成和胆固醇生物合成的抑制作用。
Antimicrob Agents Chemother. 1983 Oct;24(4):478-85. doi: 10.1128/AAC.24.4.478.
5
Oxysterols: chemical synthesis, biosynthesis and biological activities.氧化甾醇：化学合成、生物合成及生物活性
Lipids. 1986 Jan;21(1):27-30. doi: 10.1007/BF02534299.
6
Studies on the immunological properties of oxysterols: in vivo actions of 7,25-dihydroxycholesterol upon murine peritoneal cells.氧化甾醇的免疫学特性研究：7,25-二羟基胆固醇对小鼠腹腔细胞的体内作用
Immunology. 1990 Jul;70(3):344-50.