西索米星与庆大霉素对组织培养细胞作用的比较研究
[Comparative study of sisomicin and gentamycin action on the cells in a tissue culture].
作者信息
Svinogeeva T P, Berezina E K
出版信息
Antibiotiki. 1980 Apr;25(4):271-4.
PMID:7369730
Abstract
The cytostatic effect of sisomicin and gentamicin, antibiotics from the group of aminoglycosides was studied comparatively with respect to three types of tripsinized cells of chick embryo (cells of the kidneys, liver and fibroblasts). It was found that epithelial cells and in particular kidney cells were most sensitive to the above antibiotics as compared to fibroblasts. It was also shown that gentamicin had a lower cytostatic effect on the embryonal cells of the kidneys, liver and fibroblasts as compared to sisomicin.
摘要
对氨基糖苷类抗生素西索米星和庆大霉素对鸡胚的三种胰蛋白酶消化细胞（肾细胞、肝细胞和成纤维细胞）的细胞生长抑制作用进行了比较研究。结果发现，与成纤维细胞相比，上皮细胞尤其是肾细胞对上述抗生素最为敏感。研究还表明，与西索米星相比，庆大霉素对肾、肝胚胎细胞和成纤维细胞的细胞生长抑制作用较低。
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