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非黑色素瘤癌中危险因素的相对重要性。

The relative importance of risk factors in nonmelanoma carcinoma.

作者信息

Vitaliano P P, Urbach F

出版信息

Arch Dermatol. 1980 Apr;116(4):454-6.

PMID:7369779
Abstract

The relative importance of risk factors such as solar exposure, complexion, age, and the ability to tan were examined for their relationships to the development of basal and squamous cell carcinoma. Three samples were studied: patients with basal cell carcinoma (N = 366), patients with squamous cell carcinoma (N = 58), and control subjects (N = 294). The technique of logistic regression was used to estimate the relative risk of each type of carcinoma. Solar exposure was the most important risk factor for both basal and squamous cell carcinoma; however, the ability to tan was shown to be of special importance even at low levels of exposure. Given the same level of cumulative lifetime solar exposure, subjects over 60 years of age were shown to be at higher risk for nonmelanoma carcinoma than those at younger ages. Complexion was only shown to be significant for basal cell carcinoma.

摘要

研究了诸如阳光照射、肤色、年龄以及晒黑能力等风险因素与基底细胞癌和鳞状细胞癌发生发展之间的关系及其相对重要性。研究了三个样本:基底细胞癌患者(N = 366)、鳞状细胞癌患者(N = 58)和对照受试者(N = 294)。采用逻辑回归技术来估计每种类型癌症的相对风险。阳光照射是基底细胞癌和鳞状细胞癌最重要的风险因素;然而,即使在低暴露水平下,晒黑能力也显示出特别重要性。在累积终生阳光暴露水平相同的情况下,60岁以上的受试者患非黑素瘤癌的风险高于年轻受试者。肤色仅在基底细胞癌中显示出显著意义。

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