Kholodenko B N
Biofizika. 1980 Mar-Apr;25(2):250-7.
The problem of the investigation of the metabolism regulation features, which are independent of the individual variance in biochemical parameters is formulated. The glycolysis characteristic of erythrocytes which is the ATP concentration dependence of the stationary rate of the ATP production is in fact dependent also on the many individual parameters of the erythrocyte (the enzyme activities, the total sum of adenine nucleotides and so on). It is shown that this function of many variables can be effectively factorized into an universal function of the relative ATP concentration (i. e. ATP/(AMP+ADP+ATP)) and some functions of individual parameters.