Jourdan F, Duveau A, Astic L, Holley A
Brain Res. 1980 Apr 21;188(1):139-54. doi: 10.1016/0006-8993(80)90563-6.
The uptake of [14C]2-deoxy-D-glucose (2-DG) has been studied by autoradiography in the olfactory bulbs of control and odour-stimulated rats. The sites of highest 2-DG-uptake coincide very accurately with individual glomeruli. The other bulbar histological layers appear to be far less metabolically affected by the olfactory stimulation. The mapping of the glomerular activation has been compared in two groups of animals stimulated with two different odours. The patterns of selective glomerular 2-DG-uptake are rather similar within each group. They differ from one group to the other by the number and localization of the highly labelled glomeruli. It can be inferred from our observations that a few glomeruli are metabolically highly activated by a strong and pure odour stimulation. A correlation between the quality of the odour and the pattern of glomerular activation may be supposed but has to be confirmed with other compounds.
通过放射自显影术，研究了对照大鼠和经气味刺激的大鼠嗅球中[14C]2-脱氧-D-葡萄糖（2-DG）的摄取情况。2-DG摄取量最高的部位与单个肾小球非常精确地重合。嗅球的其他组织学层似乎受嗅觉刺激的代谢影响要小得多。比较了两组用两种不同气味刺激的动物肾小球激活的图谱。每组内选择性肾小球2-DG摄取模式相当相似。两组之间的差异在于高标记肾小球的数量和定位。从我们的观察中可以推断，少数肾小球在强烈而纯净的气味刺激下会发生高度代谢激活。可以推测气味质量与肾小球激活模式之间存在相关性，但必须用其他化合物加以证实。
