Casterline P F, Jaques D A, Blom H, Wartofsky L
Cancer. 1980 Apr 1;45(7):1689-92. doi: 10.1002/1097-0142(19800401)45:7<1689::aid-cncr2820450728>3.0.co;2-s.
The prognosis of giant and spindle cell carcinoma of the thyroid is extremely poor. It does appear, however, that a multisciplinary approach to treatment of this aggressive cancer is more effective than a single-treatment modality. Operative ablation of gross tumor, postoperative irradiation therapy, and chemotherapy have demonstrated encouraging results. A different therapeutic approach with the addition of immunotherapy to surgical resection, postoperative irraditation, and chemotherapy is described in this case report. The preliminary result is encouraging.
