de Bono A M, Pillers E M, Kirk N M
Br J Obstet Gynaecol. 1978 Dec;85(12):887-92. doi: 10.1111/j.1471-0528.1978.tb15849.x.
Changes in the pattern of presentation of carcinoma of the uterine cervix between 1960 and 1975 were studied using the records of 3193 patients registered with the East Anglian Cancer Registration Bureau. Between 1963 and 1968, an increased registration rate for invasive tumours was largely attributable to increased registrations of Stage I and II lesions in the 35 to 49 age group. After 1970 the registration rate for lesions of all stages in this age group declined. Over the same period the 50 to 64 age group showed a tendency for an increased proportion of registrations to be of Stage I or II lesions. There was little change in pattern in the over-65 age group. The possible relation of these changes to the introduction of a cervical cytology screening programme and the implications for future screening policies are discussed.
利用东盎格鲁癌症登记局登记的3193例患者的记录,对1960年至1975年间子宫颈癌的表现模式变化进行了研究。1963年至1968年间,浸润性肿瘤登记率的上升主要归因于35至49岁年龄组I期和II期病变登记人数的增加。1970年以后,该年龄组所有阶段病变的登记率下降。同期,50至64岁年龄组I期或II期病变登记比例有增加的趋势。65岁以上年龄组的模式变化不大。讨论了这些变化与宫颈细胞学筛查计划实施的可能关系以及对未来筛查政策的影响。