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放射自显影研究显示,肿瘤细胞中大量掺入3H-前列腺素F2α 。

Heavy incorporation of 3H-prostaglandin F2 alpha in the neoplastic cells as revealed by autoradiographic studies.

作者信息

Lupulescu A

出版信息

Experientia. 1980 Feb 15;36(2):246-7. doi: 10.1007/BF01953760.

Abstract

A marked uptake (9-fold) of the 3H-PGF2 alpha was found specifically over heterochromatin in the nuclei of neoplastic cells. Lower but significant uptakes of 3H-PGF2 alpha were also found in the nuclei of control epidermal cells, which indicate the presence of nuclear receptors in the epidermal neoplastic cells.

摘要

在肿瘤细胞核内的异染色质上发现了3H-PGF2α的显著摄取(9倍)。在对照表皮细胞核中也发现了较低但显著的3H-PGF2α摄取,这表明表皮肿瘤细胞中存在核受体。

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