放线菌素D诱导肾上腺束状带细胞的核仁分离
Induction of nucleolar segregation in adrenal fasciculata cells by actinomycin D.
作者信息
Magalhães M C, Magalhães M M
出版信息
Experientia. 1980 Mar 15;36(3):345-6. doi: 10.1007/BF01952317.
PMID:7371797
Abstract
Actinomycin D administration to young rats provokes segregation of the nucleoli of adrenal fasciculata cells into 5 distinct zones (granular, fibrillar and vacuolar zones, a fibrillar center, and a dense fibrillar or "contrasted" zone); in the cytoplasm, there were dilations of Golgi cisternae. In spite of the nucleolar segregation, the cytoplasmic alterations suggest the maintenance of protein synthesis.
摘要
给幼鼠注射放线菌素D会促使肾上腺束状带细胞的核仁分离成5个不同区域（颗粒区、纤维区和空泡区、一个纤维中心以及一个致密纤维或“对比”区）；在细胞质中，高尔基体池出现扩张。尽管存在核仁分离现象，但细胞质的变化表明蛋白质合成仍在维持。
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