Courtney K D, Ebron M T
Biol Neonate. 1978;34(3-4):203-8. doi: 10.1159/000241128.
Isozyme profiles of lactic dehydrogenase (LDH) and creatine phosphokinase (CPK) were determined in cardiac tissue of mice during postnatal development. LDH isozymes 1 and 5 showed a definite developmental change, achieving the adult values by 20 days of age, while the other three isozymes showed no change. During the first 2 postnatal weeks, a developmental change was seen in the activities of the 'mito' and MB isozymes of CPK, with the adult profile being established by day 20. CPK isozymes MM and BB did not change during this interval.
在出生后发育过程中，测定了小鼠心脏组织中乳酸脱氢酶（LDH）和肌酸磷酸激酶（CPK）的同工酶谱。LDH同工酶1和5呈现出明确的发育变化，在20日龄时达到成年值，而其他三种同工酶则无变化。在出生后的前两周，CPK的“线粒体”和MB同工酶活性出现发育变化，在20日龄时建立起成年模式。在此期间，CPK同工酶MM和BB没有变化。
