Quick C A, Anderson R, Stool S
Laryngoscope. 1980 May;90(5 Pt 1):784-91.
Three types of giant cell lesions occur in the facial skeleton; namely, giant cell reparative granuloma, Brown tumor of hyperparathyroidism, and true giant cell tumor -- osteoclastoma preferably called giant cell neoplasm. An appraisal of the clinical course biochemical laboratory data, radiographic appearance, and histological features are all necessary to distinguish between these varieties. Differentiation is a prerequisite to treatment because the management differs in each lesion. Three case reports illustrate these features. The important considerations of facial growth following surgery to the facial skeleton of a child are discussed. Long-term observation is imperative.
面部骨骼中会出现三种类型的巨细胞病变；即巨细胞修复性肉芽肿、甲状旁腺功能亢进的棕色瘤以及真正的巨细胞瘤——破骨细胞瘤，最好称为巨细胞肿瘤。评估临床病程、生化实验室数据、影像学表现和组织学特征对于区分这些类型都是必要的。鉴别是治疗的前提，因为每种病变的处理方式不同。三个病例报告说明了这些特征。本文还讨论了儿童面部骨骼手术后面部生长的重要考量因素。长期观察势在必行。
