Mertz D P
Med Klin. 1980 Feb 15;75(4):159-61.
Patients with hyperlipoproteinemia, who were treated with diet and lipid-lowering drugs, were followed up over a period of six to twelve months. The various coefficients of serum concentrations of total cholesterol, triglycerides, phospholipids, HDL-cholesterol, LDL-cholesterol, and the ratio HDL-cholesterol/total cholesterol and LDL/HDL (socalled atherosclerosis-index) were estimated. Among all factors the "atherosclerosis-index" was the most reliable indicator of an increased risk with a margin of 7,9 +/- 1,3%. The widest variation was seen, as expected, among the concentrations of triglycerides (20,1 +/- 3,0%).
接受饮食和降脂药物治疗的高脂蛋白血症患者,随访6至12个月。测定了血清总胆固醇、甘油三酯、磷脂、高密度脂蛋白胆固醇、低密度脂蛋白胆固醇的各种系数,以及高密度脂蛋白胆固醇/总胆固醇和低密度脂蛋白/高密度脂蛋白的比值(即所谓的动脉粥样硬化指数)。在所有因素中,“动脉粥样硬化指数”是风险增加最可靠的指标,误差范围为7.9±1.3%。正如预期的那样,甘油三酯浓度的变化最大(20.1±3.0%)。