Concentration of lipid, apoprotein-B and testosterone in patients with coronarographic findings.

The relationship between lipid, apolipoprotein-B and testosterone concentration and indicated coronarography was followed in male patients assigned into two age groups (under and over 50 years). Patients without a positive finding on coronary vessels served as controls. Patients of both age groups with a positive coronarographic finding showed an enhanced apolipoprotein-B and a decreased cholesterol concentration in the HDL2-high density lipoprotein subfraction. Likewise, testosterone level was also decreased in the two age groups. It appears that a lowered testosterone level may indirectly intervene into lipoprotein metabolism, or may affect the apolipoprotein-B level.