男性非特异性尿道炎的管理。六种治疗方案的评估以及包括饮酒和性行为在内的其他因素的影响。
Management of non-specific urethritis in men. Evaluation of six treatment regimens and effect of other factors including alcohol and sexual intercourse.
作者信息
Arya O P, Alergant C D, Annels E H, Carey P B, Ghosh A K, Goddard A D
出版信息
Br J Vener Dis. 1978 Dec;54(6):414-21. doi: 10.1136/sti.54.6.414.
Abstract
A trial comparing the efficacy of three different tetracyclines, each in two different dosage regimens, in the treatment of non-specific urethritis is described. There was a significant association between the retreatment rate and sexual intercourse. Age, race, duration of symptoms, previous infection, and indulgence in alcohol did not appear to influence the results whereas treatment of sexual contacts before resumption of sexual intercourse significantly reduced the retreatment rate. Single-dose treatment with doxycycline was shown to be ineffective. Treatment with doxycycline for seven days or triple tetracycline for seven days was less effective than triple tetracycline for 21 days or oxytetracyline for seven or 21 days, all of which gave the same success rate.
摘要
本文描述了一项比较三种不同四环素，每种采用两种不同给药方案，治疗非特异性尿道炎疗效的试验。再治疗率与性交之间存在显著关联。年龄、种族、症状持续时间、既往感染及饮酒情况似乎并未影响结果，而在恢复性交前对性伴侣进行治疗可显著降低再治疗率。结果表明，强力霉素单剂量治疗无效。强力霉素治疗七天或三联四环素治疗七天的效果不如三联四环素治疗21天或土霉素治疗七天或21天，而这几种治疗的成功率相同。
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本文引用的文献
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SINGLE-DOSE TREATMENT OF NON-SPECIFIC URETHRITIS.非特异性尿道炎的单剂量治疗
Br J Vener Dis. 1964 Dec;40(4):266-7. doi: 10.1136/sti.40.4.266.
2
Doxycycline treatment of nongonococcal urethritis with special reference to T-strain mycoplasmas.强力霉素治疗非淋菌性尿道炎，特别提及T株支原体。
Br J Vener Dis. 1971 Apr;47(2):126-30. doi: 10.1136/sti.47.2.126.
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Preliminary study of combined sulfametopyrazine and streptomycin single-dosage therapy in nongonococcal urethritis.
Br J Clin Pract. 1972 Apr;26(4):173-4.
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Epidemiology of urethritis in Ibadan.伊巴丹尿道炎的流行病学
Br J Vener Dis. 1972 Apr;48(2):116-20. doi: 10.1136/sti.48.2.116.
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Some highlights on the aetiology of the non-gonococcal urethral discharge in males in Kampala, Uganda.
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