非特异性尿道炎的强化及长期四环素治疗
Intensive and prolonged tetracycline therapy in non-specific urethritis.
作者信息
Helmy N, Fowler W
出版信息
Br J Vener Dis. 1975 Oct;51(5):336-9. doi: 10.1136/sti.51.5.336.
Details are given of a double-blind trial involving 400 cases in which tetracycline 500 mg. four times a day for 7 days was compared with tetracycline 250 mg. four times a day for 14 days and also of the findings in 311 cases treated with Deteclo 300 mg. three times a day for 3 weeks. The treatment in the double-blind trial were equally effective and appeared to be as effective as the long-term Deteclo therapy. When the results of these treatments were compared with those obtained previously with tetracycline 250 mg. four times a day for 4 days and allowance was made for the time at which the latter results have been assessed, it was concluded that neither the treatment used in the double-blind trial nor Deteclo 300 mg. three times a day for 3 weeks offered any advantage over the customary treatment with tetracycline 250 mg, four times a day for 4 days.
详细介绍了一项涉及400例患者的双盲试验，其中将每日4次、每次500毫克四环素治疗7天与每日4次、每次250毫克四环素治疗14天进行了比较，还介绍了311例患者使用每日3次、每次300毫克Deteclo治疗3周的结果。双盲试验中的治疗效果相当，且似乎与长期使用Deteclo治疗效果相同。当将这些治疗结果与先前每日4次、每次250毫克四环素治疗4天所获得的结果进行比较，并考虑到后者结果的评估时间时，得出的结论是，双盲试验中使用的治疗方法以及每日3次、每次300毫克Deteclo治疗3周，相较于每日4次、每次250毫克四环素的常规治疗4天，均无任何优势。
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