Baran D T, Bergfeld M A, Teitelbaum S L, Avioli L V
Calcif Tissue Res. 1978 Dec 8;26(2):103-6. doi: 10.1007/BF02013243.
Osteoporosis has been reported to complicate androgen deficiency in males. Accordingly, we have evaluated an osteoporotic hypogonadal male with bone histomorphometry before and after 6 months of testosterone replacement. Androgen therapy resulted in increases in relative osteoid volum, total osteoid surface, linear extent of bone formation, and bone mineralization. The dramatic histological response to hormonal replacement confirms the importance of androgens in bone modeling and remodeling.
据报道，骨质疏松症会使男性雄激素缺乏症复杂化。因此，我们对一名骨质疏松性腺功能减退男性在睾酮替代治疗6个月前后进行了骨组织形态计量学评估。雄激素治疗导致相对类骨质体积、总类骨质表面、骨形成线性范围和骨矿化增加。对激素替代的显著组织学反应证实了雄激素在骨塑形和重塑中的重要性。
