Aldashev A A, Igumnova T V, Servetnik-Chalaia G K
Vopr Pitan. 1980 Jan-Feb(1):38-41.
The purpose of the work was to study the effect of benzene, toluene and xylene combined with acetone on ascorbic acid (AA) supply of constructive workers exposed to prolonged C-vitaminization. Vitaminization was carried out for 6 and 12 months with various doses of AA (50, 100 and 150 mg). Additional vitaminization induced a considerable increase in AA content in the blood plasma and raised its excretion with urine in the workers given 50 and 100 mg of vitamin C and not exposed to the harmful industrial factors. In painters working in the premises with an elevated content of aromatic hydrocarbons in the air, the higher level of AA in the blood plasma and urine could be attained only after prolonged additional vitaminization at a dose of 150 mg. The data obtained in experiments on guinea pigs also indicate advisability of increasing the daily preventive dose of vitamin C under industrial conditions with an elevated content of benzene and vapours of its methyl derivatives.
这项工作的目的是研究苯、甲苯、二甲苯与丙酮的混合物对长期接受维生素C强化的建筑工人抗坏血酸（AA）供应的影响。用不同剂量的AA（50、100和150毫克）进行了6个月和12个月的维生素强化。额外的维生素强化使血浆中AA含量显著增加，并使摄入50毫克和100毫克维生素C且未接触有害工业因素的工人尿液中AA的排泄量增加。在空气中芳香烃含量较高的场所工作的油漆工中，只有在长期额外服用150毫克剂量的维生素后，血浆和尿液中的AA水平才能升高。在豚鼠身上进行的实验所获得的数据也表明，在苯及其甲基衍生物蒸汽含量较高的工业条件下，增加维生素C的每日预防剂量是可取的。
