• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

吡喹酮对微小膜壳绦虫(绦虫纲)体外作用效果的扫描电镜与透射电镜研究

Scanning and transmission electron microscope studies on the efficacy of praziquantel on Hymenolepis nana (Cestoda) in vitro.

作者信息

Becker B, Mehlhorn H, Andrews P, Thomas H

出版信息

Z Parasitenkd. 1980 Jan;61(2):121-33. doi: 10.1007/BF00925459.

DOI:10.1007/BF00925459
PMID:7376693
Abstract

The dwarf tapeworm, Hymenolepis nana, was studied by means of scanning and transmission electron microscopy after in vitro exposure to 1, 10, and 100 micrograms/ml of the anthelmintic praziquantel (Droncit) for 5, 15, 30, and 60 min. The resulting vacuolization of the tegument was exclusively confined to the neck region of the tapeworms and was already observed after treatment for 5 min with 1 microgram/ml. This vacuolization finally led to the disruption of the syncytial layer in the apical region of the tegument. The tegumental microtriches and the surface coat remained unaffected. Proglottids of the middle or posterior regions of the worms never showed destruction.

摘要

在体外将微小膜壳绦虫(Hymenolepis nana)暴露于1、10和100微克/毫升的驱虫药吡喹酮(Droncit)中5、15、30和60分钟后,通过扫描电子显微镜和透射电子显微镜对其进行了研究。由此产生的皮层空泡化仅局限于绦虫的颈部区域,在用1微克/毫升处理5分钟后就已观察到。这种空泡化最终导致皮层顶端区域的合胞体层破坏。皮层微毛和表面涂层未受影响。虫体中部或后部区域的节片从未出现破坏。

相似文献

1
Scanning and transmission electron microscope studies on the efficacy of praziquantel on Hymenolepis nana (Cestoda) in vitro.吡喹酮对微小膜壳绦虫(绦虫纲)体外作用效果的扫描电镜与透射电镜研究
Z Parasitenkd. 1980 Jan;61(2):121-33. doi: 10.1007/BF00925459.
2
Ultrastructural investigations on the effect of praziquantel on the tegument of five species of cestodes.
Z Parasitenkd. 1981;64(3):257-69. doi: 10.1007/BF00927373.
3
Light and electron microscopic studies on the effect of praziquantel on Schistosoma mansoni, Dicrocoelium dendriticum, and Fasciola hepatica (Trematoda) in vitro.吡喹酮对曼氏血吸虫、枝双腔吸虫和肝片吸虫(吸虫纲)体外作用的光镜和电镜研究
Z Parasitenkd. 1980;63(2):113-28. doi: 10.1007/BF00927527.
4
The effect of praziquantel on Hymenolepis diminuta in vitro.
Tropenmed Parasitol. 1979 Sep;30(3):391-400.
5
Comparative activity of anticestode drugs--praziquantel, niclosamide and Compound 77-6, against Hymenolepis nana.
J Helminthol. 1983 Mar;57(1):31-6. doi: 10.1017/s0022149x00007847.
6
[Ultrastructural changes of the tegument on Diphyllobothrium erinacei and Hymenolepis nana treated with paromomycin sulfate in vitro].[硫酸巴龙霉素体外作用下猬迭宫绦虫和微小膜壳绦虫皮层的超微结构变化]
Jpn J Antibiot. 1983 Mar;36(3):585-93.
7
The effect of praziquantel on the pseudophyllidean cestode Bothriocephalus acheilognathi in vitro.
Z Parasitenkd. 1985;71(5):603-8. doi: 10.1007/BF00925593.
8
Ultra structural studies of the surface of Hymenolepis nana by scanning and transmission electron microscopy.
J Egypt Soc Parasitol. 1990 Jun;20(1):47-51.
9
New results on the effect of praziquantel in experimental cysticercosis.
Am J Trop Med Hyg. 1982 Jul;31(4):803-10. doi: 10.4269/ajtmh.1982.31.803.
10
Activity of praziquantel against Hymenolepis nana, at different development stages, in experimentally infected mice.
Rev Inst Med Trop Sao Paulo. 1984 Nov-Dec;26(6):334-40. doi: 10.1590/s0036-46651984000600008.

引用本文的文献

1
Preclinical Evaluations of Modified Rice Hydrogel for Topical Ophthalmic Drug Delivery of Praziquantel on Avian Philophalmiasis.用于吡喹酮局部眼部给药治疗禽类嗜眼吸虫病的改性水稻水凝胶的临床前评估
Pharmaceutics. 2021 Jun 24;13(7):952. doi: 10.3390/pharmaceutics13070952.
2
In vitro effects of lonidamine and 6-aminonicotinamide against Echinococcus granulosussensu stricto and Echinococcus multilocularis.体外洛尼哒胺和 6-氨基烟酰胺对细粒棘球蚴和多房棘球绦虫的作用。
Vet Res. 2020 Feb 26;51(1):29. doi: 10.1186/s13567-020-00744-6.
3
Surface histology, topography, and ultrastructure of the tegument of adult Orthocoelium parvipapillatum (Stiles & Goldberger, 1910).

本文引用的文献

1
Cytological studies on the absorptive surfaces of cestodes. I. The fine structure of the strobilar integument.绦虫吸收表面的细胞学研究。I. 节片外皮的精细结构。
Z Parasitenkd. 1966;27(4):355-82. doi: 10.1007/BF00260034.
2
Microtrichial polymorphism among hymenolepid tapeworms as seen by scanning electron microscopy.
Trans Am Microsc Soc. 1971 Oct;90(4):393-403.
3
Preparation of animal tissues for surface-scanning electron microscopy.用于表面扫描电子显微镜的动物组织制备
J Microsc. 1969;90(3):221-49. doi: 10.1111/j.1365-2818.1969.tb00709.x.
微小乳头直腔吸虫(斯泰尔斯和戈德伯格,1910年)成虫皮层的表面组织学、形态学及超微结构
Parasitol Res. 2016 Jul;115(7):2757-69. doi: 10.1007/s00436-016-5024-3. Epub 2016 Mar 28.
4
The effect of praziquantel and Carica papaya seeds on Hymenolepis nana infection in mice using scanning electron microscope.扫描电子显微镜观察吡喹酮和番木瓜籽对感染微小膜壳绦虫小鼠的作用。
Parasitol Res. 2014 Aug;113(8):2827-36. doi: 10.1007/s00436-014-3943-4. Epub 2014 May 22.
5
Praziquantel treatment in trematode and cestode infections: an update.吡喹酮治疗吸虫和绦虫感染:最新进展。
Infect Chemother. 2013 Mar;45(1):32-43. doi: 10.3947/ic.2013.45.1.32. Epub 2013 Mar 29.
6
Cassia alata L: potential role as anthelmintic agent against Hymenolepis diminuta.亚麻子:作为抗猪带绦虫药物的潜在作用。
Parasitol Res. 2012 Sep;111(3):1187-92. doi: 10.1007/s00436-012-2950-6. Epub 2012 May 11.
7
Effect of praziquantel treatment of Schistosoma mansoni during pregnancy on intensity of infection and antibody responses to schistosome antigens: results of a randomised, placebo-controlled trial.孕期用吡喹酮治疗曼氏血吸虫对感染强度及血吸虫抗原抗体反应的影响:一项随机、安慰剂对照试验的结果
BMC Infect Dis. 2009 Mar 18;9:32. doi: 10.1186/1471-2334-9-32.
8
Time course of the effect of praziquantel on Schistosoma mansoni attachment in vitro: comparison with its effects on worm length and motility.吡喹酮对曼氏血吸虫体外附着作用的时间进程:与其对虫体长度和活力影响的比较
Parasitol Res. 1995;81(7):543-8. doi: 10.1007/BF00932019.
9
Light and electron microscopic studies on the effect of praziquantel on Schistosoma mansoni, Dicrocoelium dendriticum, and Fasciola hepatica (Trematoda) in vitro.吡喹酮对曼氏血吸虫、枝双腔吸虫和肝片吸虫(吸虫纲)体外作用的光镜和电镜研究
Z Parasitenkd. 1980;63(2):113-28. doi: 10.1007/BF00927527.
10
Effect of praziquantel on adult Echinococcus granulosus in vitro: scanning electron microscopy.吡喹酮对体外细粒棘球绦虫成虫的作用:扫描电子显微镜观察
Z Parasitenkd. 1981;66(2):191-9. doi: 10.1007/BF00925726.
4
Brush border development in the tegument of the tapeworm, Spirometra mansonoides.
J Parasitol. 1974 Apr;60(2):209-26.
5
Surface topography of Hymenolepis diminuta by scanning electron microscopy.
J Parasitol. 1973 Aug;59(4):667-71.
6
Taenia hydatigena. IV. Ultrastructure study of the tegument.
Z Parasitenkd. 1972;38(3):214-32. doi: 10.1007/BF00329599.
7
Morphological changes in cysticerci of Taenia taeniaeformis after mebendazole treatment.
J Parasitol. 1975 Oct;61(5):830-43.
8
Cytochemical characterization of tegument membrane-associated carbohydrates in Taenia crassiceps larvae.
J Parasitol. 1975 Aug;61(4):665-76.
9
The efficacy of praziquantel against cestodes in animals.吡喹酮对动物体内绦虫的疗效。
Z Parasitenkd. 1977 Jul 21;52(2):117-27. doi: 10.1007/BF00389898.
10
Metabolic gradient in Hymenolepis diminuta under aerobic conditions.
Int J Parasitol. 1977 Apr;7(2):127-8. doi: 10.1016/0020-7519(77)90079-0.