Becker B, Mehlhorn H, Andrews P, Thomas H
Z Parasitenkd. 1980 Jan;61(2):121-33. doi: 10.1007/BF00925459.
The dwarf tapeworm, Hymenolepis nana, was studied by means of scanning and transmission electron microscopy after in vitro exposure to 1, 10, and 100 micrograms/ml of the anthelmintic praziquantel (Droncit) for 5, 15, 30, and 60 min. The resulting vacuolization of the tegument was exclusively confined to the neck region of the tapeworms and was already observed after treatment for 5 min with 1 microgram/ml. This vacuolization finally led to the disruption of the syncytial layer in the apical region of the tegument. The tegumental microtriches and the surface coat remained unaffected. Proglottids of the middle or posterior regions of the worms never showed destruction.
在体外将微小膜壳绦虫(Hymenolepis nana)暴露于1、10和100微克/毫升的驱虫药吡喹酮(Droncit)中5、15、30和60分钟后,通过扫描电子显微镜和透射电子显微镜对其进行了研究。由此产生的皮层空泡化仅局限于绦虫的颈部区域,在用1微克/毫升处理5分钟后就已观察到。这种空泡化最终导致皮层顶端区域的合胞体层破坏。皮层微毛和表面涂层未受影响。虫体中部或后部区域的节片从未出现破坏。