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癫痫及其他影响胶质瘤预后的因素。

Epilepsy and other factors in the prognosis of gliomas.

作者信息

Scott G M, Gibberd F B

出版信息

Acta Neurol Scand. 1980 Apr;61(4):227-39. doi: 10.1111/j.1600-0404.1980.tb01487.x.

DOI:10.1111/j.1600-0404.1980.tb01487.x
PMID:7376822
Abstract

A study of 95 patients with gliomas has been made. The 50% survival was 15 months after the first symptom. At the time of presentation all patients had an abnormal brain scan and E.E.G. except some of those who presented with epilepsy. The patients with epilepsy had a significantly better prognosis than those without and this was not due to their having less malignant tumours according to histological appearance. Other factors which were associated with significantly longer survival were a younger age at presentation, partial removal of the tumour rather than biopsy or no operation, lower histological grades of tumour and treatment with radiotherapy or chemotherapy.

摘要

对95例胶质瘤患者进行了一项研究。首次出现症状后,50%的患者生存期为15个月。就诊时,所有患者的脑部扫描和脑电图均异常,但部分以癫痫为首发症状的患者除外。有癫痫症状的患者预后明显好于无癫痫症状的患者,且根据组织学表现,这并非由于他们的肿瘤恶性程度较低所致。与生存期显著延长相关的其他因素包括就诊时年龄较小、肿瘤部分切除而非活检或未手术、肿瘤组织学分级较低以及接受放疗或化疗。

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