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掺入饲料中的甲氧基取代甘油醚对各种实验性肿瘤-宿主系统的作用。

Action on various experimental tumour-host systems of methyoxy-substituted glycerol ethers incorporated into the feed.

作者信息

Boeryd B, Hallgren B

出版信息

Acta Pathol Microbiol Scand A. 1980 Jan;88(1):11-8. doi: 10.1111/j.1699-0463.1980.tb02460.x.

Abstract

The effect of the growth and spread of tumours by methoxy-substituted glycerol ethers incorporated into the feed has been tested on a broad spectrum of tumour-host systems. Inhibitory effects on tumour growth were noted mainly by 1-0-(2-methoxy-hexadecyl) glycerol and on Melanoma B 16, Lewis Lung Tumour, MCA-sarcoma MCG101 and the lymphomas LAA and P1534. Spontaneous metastasis formation from Melanoma B16 and two MCA-sarcomas was inhibited.

摘要

已在多种肿瘤宿主系统中测试了饲料中添加的甲氧基取代甘油醚对肿瘤生长和扩散的影响。主要观察到1-0-(2-甲氧基十六烷基)甘油对黑色素瘤B16、刘易斯肺癌、MCA肉瘤MCG101以及淋巴瘤LAA和P1534的肿瘤生长有抑制作用。黑色素瘤B16和两种MCA肉瘤的自发转移形成受到抑制。

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