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加热在大鼠无创血压测量中的作用。

Role of heating in non-invasive blood pressure measurements in rats.

作者信息

Borg E, Viberg A

出版信息

Acta Physiol Scand. 1980 Jan;108(1):73-5. doi: 10.1111/j.1748-1716.1980.tb06501.x.

DOI:10.1111/j.1748-1716.1980.tb06501.x
PMID:7376906
Abstract

The "tail-cuff" technique for indirect blood pressure measurements was standardized, with respect to heating, in experiments on 47 adult Sprague-Dawley rats. The direct, intra-arterial, and the indirect blood pressures were simultaneously obtained. Pulse volume was recorded from the tail by a non-invasive technique, and was controlled by gradual application of heat. It was found that pulse volume and body temperature were poorly related. A stable relation existed, however, between the error in the indirect blood pressure recordings and the pulse volume. The error was minimized, provided that the heating was adjusted to induce a pulse volume of at least 25% of the maximum obtainable value. It was suggested that the validity of the indirect blood pressure recording could be improved, if heat application was regulated on the basis of observations of pulse volume in the tail instead of ambient temperature or body temperature. Errors due to excessive vasoconstriction, or discomfort due to overheating could thereby be minimized.

摘要

在对47只成年斯普拉格-道利大鼠进行的实验中,针对加热环节,对用于间接血压测量的“尾套”技术进行了标准化。同时获取了直接动脉内血压和间接血压。通过一种非侵入性技术记录尾部的脉搏容积,并通过逐渐加热进行控制。结果发现脉搏容积与体温之间的相关性较差。然而,间接血压记录中的误差与脉搏容积之间存在稳定的关系。如果将加热调节至使脉搏容积至少达到可获得的最大值的25%,则误差可降至最低。有人提出,如果根据尾部脉搏容积的观察结果而非环境温度或体温来调节加热,那么间接血压记录的有效性可能会得到提高。由此可以将因过度血管收缩导致的误差或因过热引起的不适降至最低。

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Intra-arterial pressure alterations during tail-cuff blood pressure measurements in normotensive and hypertensive rats.正常血压和高血压大鼠尾袖带血压测量期间的动脉内压力变化
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