Capstick N
Acta Psychiatr Scand. 1980 Mar;61(3):256-62. doi: 10.1111/j.1600-0447.1980.tb00875.x.
Forty-seven schizophrenic out-patients, who were satisfactorily maintained on a depot injection of fluphenazine decanoate, and who received the injection every 28 days, were progressively withdrawn from medication by increasing the time interval between injections while maintaining the amount of of drug per injection. The rate of reduction varied with each patient depending on various factors such as environmental stress considerations, and the patient's wishes. Finally three injections at 8-weekly intervals were given before complete withdrawal. The follow-up period was 23.7 months with a standard deviation of 1.9. A relapse rate of 80% was found, 25 patients relapsing during the withdrawal phase and 22 patients after the drug had been completely withdrawn.
47名精神分裂症门诊患者，他们通过癸酸氟奋乃静长效注射剂得到了满意的维持治疗，且每28天接受一次注射，在保持每次注射药物量不变的情况下，通过增加注射间隔时间逐步停药。减药速度因患者而异，取决于各种因素，如环境压力因素和患者意愿。最后，在完全停药前每8周注射一次，共注射三次。随访期为23.7个月，标准差为1.9。发现复发率为80%，25名患者在减药阶段复发，22名患者在药物完全停用后复发。
