Iqbal M J, Young M A, Charles J, Elgart B, Von Greiff H, Simpson G M
J Clin Psychiatry. 1978 Apr;39(4):375-9.
Penfluridol, a diphenylbutylpiperidene derivative, is a new long acting neuroleptic, administered orally, once weekly. It is marketed in several European countries and has been used successfully in the treatment of various acute psychoses, for severely ill chronic schizophrenic patients, and as maintenance therapy for chronic schizophrenic patients. The present study was designed to compare, in a double-blind fashion, the efficacy of penfluridol and fluphenazine decanoate in the maintenance therapy of schizophrenic outpatients.
五氟利多是一种二苯基丁基哌啶衍生物，是一种新型长效抗精神病药物，每周口服一次。它在几个欧洲国家上市，并已成功用于治疗各种急性精神病、重症慢性精神分裂症患者以及作为慢性精神分裂症患者的维持治疗。本研究旨在以双盲方式比较五氟利多和癸酸氟哌啶醇在精神分裂症门诊患者维持治疗中的疗效。
