Feinberg L E
Am Fam Physician. 1980 Jun;21(6):83-6.
Patients with symptomatic duodenal ulcer can be effectively treated with antacids or cimetidine. Many patients with a first episode or an occasional flare-up of ulcer disease should be treated with antacids. Cimetidine should be added if the response is unsatisfactory. Cimetidine should be used initially in patients with severe ulcer diathesis and in those with conditions such as diarrheal disease or chronic renal failure that predispose to troublesome side effects from antacids. For most patients, chronic cimetidine therapy after healing of the ulcer is not warranted. Exceptions are those with severe and complicated disease.
有症状的十二指肠溃疡患者可用抗酸剂或西咪替丁进行有效治疗。许多首次发作或偶尔溃疡病发作的患者应以抗酸剂治疗。如果疗效不令人满意，则应加用西咪替丁。对于有严重溃疡素质的患者以及患有诸如腹泻病或慢性肾衰竭等疾病、易因抗酸剂产生麻烦副作用的患者，应首先使用西咪替丁。对于大多数患者而言，溃疡愈合后无需进行长期的西咪替丁治疗。严重和复杂疾病患者除外。
