Attar S, Lee Y C, Singleton R, Scherlis L, David R, McLaughlin J S
Ann Thorac Surg. 1980 May;29(5):397-405. doi: 10.1016/s0003-4975(10)61667-0.
Ten patients with cardiac myxoma were reviewed. The ranged from 23 months to 60 years old. Echocardiography was the most helpful noninvasive diagnostic technique. The tumor was demonstrated by angiocardiography, left atrial myxomas frequently migrating to the left ventricle in diastole. Hemodynamically, left atrial myxomas were associated with moderately severe pulmonary hypertension and simulated mitral stenosis or insufficiency and right atrial myxomas, with right atrial hypertension. There were 7 myxomas in the left atrium, 2 in the right atrium, and 1 in the right ventricle. Eight patients underwent open-heart operation with removal of the myxoma, 1 had concomitant tricuspid valve replacement, and 1 had biopsy of the right ventricle only. The other patient was a Jehovah's Witness and refused operation. One patient died of cardiac arrest intraoperatively, and another died of a bilateral cerebral infarct. One patient had recurrence requiring reoperation. Postoperative hemodynamic and clinical improvement was more striking in patients with a left atrial myxoma presumably due to a normal mitral valve in contradistinction to the tricuspid valve.
对10例心脏黏液瘤患者进行了回顾性研究。患者年龄从23个月至60岁不等。超声心动图是最有用的非侵入性诊断技术。心血管造影可显示肿瘤,左心房黏液瘤在舒张期常移至左心室。在血流动力学方面,左心房黏液瘤与中度严重的肺动脉高压相关,可模拟二尖瓣狭窄或关闭不全,而右心房黏液瘤与右心房高压相关。左心房有7例黏液瘤,右心房有2例,右心室有1例。8例患者接受了心脏直视手术切除黏液瘤,1例同时进行了三尖瓣置换,1例仅对右心室进行了活检。另1例患者是耶和华见证会成员,拒绝手术。1例患者术中死于心脏骤停,另1例死于双侧脑梗死。1例患者复发需要再次手术。左心房黏液瘤患者术后血流动力学和临床改善更为显著,推测这是由于二尖瓣正常,与三尖瓣情况不同。