Hayes J D, Strange R C, Percy-Robb I W
Biochem J. 1980 Jan 1;185(1):83-7. doi: 10.1042/bj1850083.
Cholic acid-binding activity in cytosol from rat livers appears to be mainly associated with enzymes having glutathione S-transferase activity; at least four of the enzymes in this group can bind the bile acid. Examination of the subunit compositions of different glutathione S-transferases indicated that cholic acid binding and the ability to conjugate reduced glutathione with 1,2-dichloro-4-nitrobenzene may be ascribed to different subunits.
大鼠肝脏胞液中的胆酸结合活性似乎主要与具有谷胱甘肽S-转移酶活性的酶相关;该组中至少有四种酶可以结合胆汁酸。对不同谷胱甘肽S-转移酶亚基组成的研究表明,胆酸结合以及将还原型谷胱甘肽与1,2-二氯-4-硝基苯结合的能力可能归因于不同的亚基。