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大鼠体内谷胱甘肽S-转移酶多种形式的组织分布及亚基结构

Tissue distribution and subunit structures of the multiple forms of glutathione S-transferase in the rat.

作者信息

Scully N C, Mantle T J

出版信息

Biochem J. 1981 Jan 1;193(1):367-70. doi: 10.1042/bj1930367.

DOI:10.1042/bj1930367
PMID:7305931
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1162609/
Abstract

A study of the subunit structures of the multiple forms of glutathione S-transferase in rat kidney, testis, lung and spleen is shown to be consistent with a proteolytic model for the generation of the multiple forms.

摘要

一项关于大鼠肾脏、睾丸、肺和脾脏中谷胱甘肽S-转移酶多种形式的亚基结构的研究表明，其与多种形式产生的蛋白水解模型一致。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8255/1162609/b183baf8e583/biochemj00408-0358-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8255/1162609/b183baf8e583/biochemj00408-0358-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8255/1162609/b183baf8e583/biochemj00408-0358-a.jpg

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Biochem J. 1981 Jan 1;193(1):367-70. doi: 10.1042/bj1930367.
2
Use of immuno-blot techniques to discriminate between the glutathione S-transferase Yf, Yk, Ya, Yn/Yb and Yc subunits and to study their distribution in extrahepatic tissues. Evidence for three immunochemically distinct groups of transferase in the rat.使用免疫印迹技术区分谷胱甘肽S-转移酶Yf、Yk、Ya、Yn/Yb和Yc亚基，并研究它们在肝外组织中的分布。大鼠体内存在三种免疫化学性质不同的转移酶组的证据。
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Biochem Int. 1986 Jul;13(1):65-9.
4
Acidic glutathione S-transferases of rat testis.大鼠睾丸的酸性谷胱甘肽S-转移酶
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引用本文的文献

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Purification and characterization of three forms of glutathione S-transferase A. A comparative study of the major YaYa-, YbYb- and YcYc-containing glutathione S-transferases.三种形式谷胱甘肽S-转移酶A的纯化与特性分析。含主要YaYa-、YbYb-和YcYc-的谷胱甘肽S-转移酶的比较研究。
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A study of the structures of the YaYa and YaYc glutathione S-transferases from rat liver cytosol. Evidence that the Ya monomer is responsible for lithocholate-binding activity.

本文引用的文献

1
Studies on the nature of the multiple forms of the glutathione S-transferases.谷胱甘肽S-转移酶多种形式的性质研究。
Biochem Soc Trans. 1980 Aug;8(4):451-2. doi: 10.1042/bst0080451.
2
Cholic acid binding by glutathione S-transferases from rat liver cytosol.大鼠肝细胞溶质谷胱甘肽S-转移酶与胆酸的结合
Biochem J. 1980 Jan 1;185(1):83-7. doi: 10.1042/bj1850083.
3
Subunit composition, organic anion binding, catalytic and immunological properties of ligandin from rat testis.大鼠睾丸中配体蛋白的亚基组成、有机阴离子结合、催化及免疫学特性
大鼠肝细胞溶质中YaYa和YaYc谷胱甘肽S-转移酶结构的研究。Ya单体负责石胆酸结合活性的证据。
Biochem J. 1981 Aug 1;197(2):491-502. doi: 10.1042/bj1970491.
4
Selective induction of glutathione S-transferase D in rat testis by phenobarbital.苯巴比妥对大鼠睾丸中谷胱甘肽S-转移酶D的选择性诱导作用。
Biochem J. 1984 Apr 15;219(2):687-8. doi: 10.1042/bj2190687.
5
Evidence for two forms of ligandin (YaYa dimers of glutathione S-transferase) in rat liver and kidney.大鼠肝脏和肾脏中两种形式的配体蛋白（谷胱甘肽S-转移酶的YaYa二聚体）的证据。
Biochem J. 1984 Mar 15;218(3):893-7. doi: 10.1042/bj2180893.
6
Bile acid inhibition of basic and neutral glutathione S-transferases in rat liver.胆汁酸对大鼠肝脏中碱性和中性谷胱甘肽S-转移酶的抑制作用。
Biochem J. 1983 Dec 1;215(3):581-8. doi: 10.1042/bj2150581.
7
Rat liver glutathione S-transferases. A study of the structure of the basic YbYb-containing enzymes.大鼠肝脏谷胱甘肽S-转移酶。对含基本YbYb的酶的结构研究。
Biochem J. 1983 Sep 1;213(3):625-33. doi: 10.1042/bj2130625.
8
Two immunologically distinct Yc-type subunits are present in rat lung glutathione S-transferases.大鼠肺谷胱甘肽S-转移酶中存在两种免疫上不同的Yc型亚基。
Biochem J. 1984 Nov 15;224(1):335-8. doi: 10.1042/bj2240335.
9
Rat lung glutathione S-transferases. Evidence for two distinct types of 22000-Mr subunits.大鼠肺谷胱甘肽S-转移酶。存在两种不同类型的22000道尔顿亚基的证据。
Biochem J. 1984 Aug 1;221(3):609-15. doi: 10.1042/bj2210609.
10
Immunochemical localization of glutathione S-transferases in rat lung.
Lung. 1984;162(5):305-13. doi: 10.1007/BF02715661.
J Biol Chem. 1980 Jan 25;255(2):724-7.
4
Structural, catalytic, binding, and immunological properties associated with each of the two subunits of rat liver ligandin.
J Biol Chem. 1980 Jan 25;255(2):718-23.
5
Studies of Y and Z, two hepatic cytoplasmic organic anion-binding proteins: effect of drugs, chemicals, hormones, and cholestasis.对两种肝脏细胞质有机阴离子结合蛋白Y和Z的研究：药物、化学物质、激素及胆汁淤积的影响
J Clin Invest. 1971 Nov;50(11):2242-52. doi: 10.1172/JCI106721.
6
Two hepatic cytoplasmic protein fractions, Y and Z, and their possible role in the hepatic uptake of bilirubin, sulfobromophthalein, and other anions.两种肝细胞质蛋白组分Y和Z及其在肝脏摄取胆红素、磺溴酞钠和其他阴离子中的可能作用。
J Clin Invest. 1969 Nov;48(11):2156-67. doi: 10.1172/JCI106182.
7
Immunological studies of Y protein. A major cytoplasmic organic anion-binding protein in rat liver.Y蛋白的免疫学研究。大鼠肝脏中的一种主要细胞质有机阴离子结合蛋白。
J Clin Invest. 1972 Mar;51(3):677-84. doi: 10.1172/JCI106856.
8
Glutathione S-transferases. The first enzymatic step in mercapturic acid formation.谷胱甘肽S-转移酶。硫醚氨酸形成过程中的首个酶促步骤。
J Biol Chem. 1974 Nov 25;249(22):7130-9.
9
Isoelectric focusing of glutathione S-transferases from rat liver and kidney.大鼠肝脏和肾脏中谷胱甘肽S-转移酶的等电聚焦
Biochem J. 1978 Dec 1;175(3):937-43. doi: 10.1042/bj1750937.
10
Interpretation of the difference index as a guide to protein sequence identity.将差异指数解释为蛋白质序列同一性的指导。
J Theor Biol. 1978 Sep 21;74(2):155-61. doi: 10.1016/0022-5193(78)90068-1.