Chui D H, Patterson M, Bayley S T
Br J Haematol. 1980 Mar;44(3):431-9. doi: 10.1111/j.1365-2141.1980.tb05913.x.
Messenger RNA (mRNA) was isolated from adult as well as normal and mutant f/f fetal mouse reticulocytes by poly-U affinity chromatography. mRNA from normal adult reticulocytes directed equal synthesis of alpha and beta globin chains in wheat germ cell free translational system. mRNA from either normal or mutant f/f fetal reticulocytes directed 40% more alpha globin synthesis than beta globin synthesis. These observations are suggestive that there is significantly more alpha mRNA than beta mRNA in normal and mutant f/f fetal mouse reticulocytes.
通过聚-U亲和层析从成年以及正常和突变型f/f胎鼠网织红细胞中分离出信使核糖核酸（mRNA）。在小麦胚芽无细胞翻译系统中，正常成年网织红细胞的mRNA指导α和β珠蛋白链的等量合成。正常或突变型f/f胎鼠网织红细胞的mRNA指导的α珠蛋白合成比β珠蛋白合成多40%。这些观察结果提示，在正常和突变型f/f胎鼠网织红细胞中，α mRNA明显多于β mRNA。
