Beliaeva N N, Bonashevskaia T I, Nekrasova G I
Biull Eksp Biol Med. 1980;89(1):57-9.
Polyploidization of hepatocytes in albino rats subjected to continuous and intermittent exposure to CCl4 has been studied karyometrically. It has been shown that polyploidization as a response to the exposure of chlorderivatives of hydrocarbons is determined by hepatotoxin toxicity related to the number of chlorine atoms in the molecule and to the character of the exposure involving route, dose and regimen of exposure.
已采用核测量法研究了连续和间歇接触四氯化碳的白化病大鼠肝细胞的多倍体化情况。结果表明，作为对烃类氯衍生物接触的一种反应，多倍体化取决于与分子中氯原子数量以及涉及接触途径、剂量和接触方案的接触特性相关的肝毒素毒性。
