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[多种应激事件及随后四氯化碳中毒过程中不同遗传品系小鼠肝实质的结构变化]

[Structural changes in the liver parenchyma of mice of various genetic strains during multiple stressful events and subsequent CCl4 poisoning].

作者信息

Shkurupiĭ V A

出版信息

Tsitol Genet. 1986 Jul-Aug;20(4):251-6.

PMID:3765103
Abstract

The preliminary state of long-term stress decreases the liver resistance to the action of CCl4 in mice of two different strains and delays the process of repair of the liver parenchyma after its damage. The development of these processes has certain peculiarities in mice of each strain, that testifies to the importance of genetic factors in determination of the liver response to stress and damaging effect.

摘要

长期应激的初始状态会降低两种不同品系小鼠肝脏对四氯化碳作用的抵抗力，并延缓肝实质损伤后的修复过程。这些过程的发展在每个品系的小鼠中都有一定的特点，这证明了遗传因素在决定肝脏对应激和损伤作用反应中的重要性。

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